Connection One professors Junseok Chae and Bertan Bakkaloglu received an Semiconductor Research Consortium (SRC) Cross-Disciplinary Semiconductor Research (CSR) Program entitled "A Disposable Integrated CMOS Biosensor for Pre-screening of Cardiovascular Diseases". Fibrinogen is one of many biomarkers for cardiovascular diseases such as stroke, carotid atherosclerosis, and endocarditis. All existing methods to detect fibrinogen including Clauss method, gravimetry, and nephelometry are time consuming, costly, and require very experienced personnel to operate. In order to overcome these limitations the proposed biosensor takes advantage of high accuracy, high speed monolithic CMOS circuitry, disposable chips removing the need to clean and reset sensors, and fully automated electronic processing. In 2005, the cost of heart disease and stroke in the United States exceed $394 billion: $242 billion for health care expenditures and $152 billion for lost productivity from death and disability. In 2001, the cost of hospitalization for cardiovascular problems among Medicare beneficiaries topped $29 billion.

Dr. Bakkaloglu & Dr. Chae